U-44069

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U 44069 U44069

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U-44069 is a stable analog of the endoperoxide PGH2 and a TP receptor agonist. It stimulates shape change in human platelets without a measurable increase in [Ca2+] with EC50 value of 1.8 nM. U-44069 has an EC50 value of 3 μM and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively.

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