YF-2 hydrochloride

YF-2 hydrochloride

YF-2 hydrochloride

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  • Purity: 95%

Keywords

Benzamide, N-(4-chloro-3-(trifluoromethyl)phenyl)-2-(2-(dimethylamino)ethoxy)-6-ethoxy-, hydrochloride (1:1)

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YF-2 hydrochloride is a highly selective and blood-brain-barrier permeable activator of histone acetyltransferase (HAT) that acetylates H3 in the hippocampus, with EC50s of 2.75, 29.04 and 49.31 μM for CBP, PCAF and GCN5, respectively. It has anti-cancer and anti-Alzheimer's effects.

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