7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

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Purity: 95%

Keywords

Gefitinib Impurity 12 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one

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Appearance:White to Off-white Solid
Application:For research use only.
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Storage:Store at 2-8°C
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We provide customized and high-quality 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one product for your project.

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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is an intermediate of Gefitinib. Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition.

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