FR901512

FR901512

FR901512

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  • Purity: 95%

Keywords

6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)- (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid

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FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells.

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