Antibiotic 333-25 Octapeptin A1, 1-(N(sup 2)-(3-hydroxy-6-methyl-1-oxooctyl)-D-2,4-diaminobutanoic acid)-4-D-phenylalanine-
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It is a peptide antibiotic produced by the strain of Bacillus circulans 333-25. It has anti-gram-positive and gram-negative bacteria activity, but no effect on pseudomonas aeruginosa. It inhibits E. coli and Klebsiella pneumoniae with IC50 of 0.95 mg/kg (
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