Adenosine-5'-diphos...

Adenosine-5'-diphosphate     58-64-0
Adenosine-5'-diphosphate     58-64-0
Adenosine-5'-diphosphate     58-64-0
Adenosine-5'-diphosphate     58-64-0
Adenosine-5'-diphosphate     58-64-0

Adenosine-5'-diphosphate 58-64-0

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 1.0000 -10.0000

  • Min.Order :1 Kilogram
  • Purity: >99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

5'-Pyrophosphate, Adenosine ADENOSINE 5'-DIPHOSPHATE Adenosine 5' Pyrophosphate

Quick Details

  • Appearance:White
  • Application: is a central component of energy storage, metabolism, and signal transduction in vivo.
  • PackAge:In plastic outside weave or according to your request
  • ProductionCapacity:500|Kilogram|Week
  • Storage:-15°C
  • Transportation:We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.?

Superiority:

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details:

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molar Mass 427.2
Density 2.49±0.1 g/cm3(Predicted)
Melting Point >145oC (dec.)
Boling Point 196°C
Solubility Soluble in water
Appearance White crystal or powder
Color White to Off-White
Merck 13,155
BRN 67722
pKa pK2: 4.2(-1);pK3: 7.20(-2) (25°C)
Storage Condition -20°C
Sensitive Easily absorbing moisture
MDL MFCD00066473
In vitro study Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.
high-energy phosphate compounds Adenosine diphosphate is also called adenosine diphosphate. A high-energy phosphoric acid compound. Adenosine diphosphate (ADP) is a central component of energy storage, metabolism and signal transduction in vivo. It is the precursor of ATP, under which it is widely used in cellular processes, including respiration, biosynthetic reactions, movement and cell division. Two phosphoryl groups are linked by a pyrophosphate bond and then linked by a phosphate bond to adenosine 51-c. The structural formula is shown in Figure 1. It can be hydrolyzed to produce adenosine monophosphate (AMP) and phosphoric acid, and the standard free energy change of the reaction is -27.2 kJ · mol-1. In vivo, can be produced by adenosine triphosphate (ATP) hydrolysis or phosphoryl transfer to remove a phosphate. In general tissues, it can be phosphorylated at the substrate level and oxidative phosphorylation, and in photosynthetic tissues, it can also be transformed into ATP by photosynthetic phosphorylation. 1 shows the structural formula of adenosine diphosphate.
Adenosine phosphate Adenosine phosphate, also known as adenosine phosphate, is linked to phosphate by adenine nucleoside through its ribose group, A free-occurring nucleotide synthesized in the body, the adenosine monophosphate (AMP), which contains a phosphate group of the Adenosine nucleotide, adenosine diphosphate (ADP), adenosine triphosphate (ATP), the binding bond between phosphoric acid and phosphoric acid contains high energy called high energy phosphate bonds. Each gram of high-energy phosphate bond contains about 8000 calories, and the energy stored by these high-energy phosphate bonds can be used for the needs of biological anabolism, muscle contraction and other life activities. The clinical application of adenosine triphosphate injection is suitable for a variety of diseases caused by the decrease of cell enzyme after cell injury. Commonly used in heart failure, myocarditis, myocardial infarction, cerebral arteriosclerosis and progressive muscular atrophy disease.
nucleotide a nucleotide is a phosphate ester formed by condensation of a nucleoside with a phosphate. Depending on the content of ribose, they are called ribonucleotides and deoxyribonucleotides. Ribose has three free hydroxyl groups (2 ', 3', 5 'positions), so it can form three nucleotides, referred to as 2'-nucleotides, 3 '-nucleotide and 5'-nucleotide. Deoxyribose has two free hydroxyl groups, 3 'and 5', and therefore only 3 '-deoxynucleotides and 5'-deoxynucleotides. Nucleotides are the monomers that make up ribonucleic acid and deoxyribonucleic acid.
Each nucleotide contains only one molecule of phosphate, which is called nucleoside monophosphate, for example, adenosine monophosphate (AMP) is also called adenosine monophosphate. If it contains two or three phosphate molecules, they are called adenosine diphosphate (ADP) and adenosine triphosphate (ATP), the latter end of the phosphate is prone to hydrolysis and cleavage and release of energy, commonly referred to as high-energy phosphate bonds. ADP is formed after ATP is dephosphorylated, and the phosphorylation of ADP in the process of cell respiration can generate ATP. Others like guanosine triphosphate (GTP), Cytidine triphosphate (CTP) and uridine triphosphate (UTP) are also indispensable substances in cell metabolism and energy transport. Some cyclic adenylic acid and guanosine monophosphate are also found in the cells, which are caused by ATP and GTP under the action of adenylate cyclase and guanylate cyclase respectively, A 3 ', 5'-nucleoside phosphate produced by the loss of a dimolecular phosphate. Cyclic adenosine monophosphate (cAMP) is a common mediator of the actions of many hormones within the cell, a "second messenger" of the action of hormones (first messengers) ". The hormone acts on the specific receptor on the cell membrane, activates adenylate cyclase, and under the action of adenylate cyclase, ATP generates cAMP, which activates protein kinase, under the action of protein kinase, the activation or generation of some enzymes is affected, and the regulation of substance metabolism is realized, thus producing the corresponding physiological function. cGMP is also an important substance in the regulation of metabolism in cells. They rely on a very fine balance between them to maintain and control the normal growth of cells.
Figure 2 shows the role of various nucleotides in substance metabolism.
Energy metabolism Energy Metabolism refers to the process of energy production and consumption in the process of material metabolism (metabolism). The direct source of energy for muscle activity is the breakdown of adenosine triphosphate (ATP), and the ultimate source is the breakdown of sugar or fat. ATP in muscle is rapidly decomposed into adenosine diphosphate (ADP) and inorganic phosphate under the action of enzymes, and energy is released at the same time. This energy is the only direct energy source for muscle contraction (activity). But the muscle's ATP reserve is very small, so it must be decomposed and synthesized, in order to make the muscle activity lasting. In fact, as soon as adenosine triphosphate is decomposed, it is synthesized immediately from other products. When adenosine diphosphate is present in the muscle, another high-energy phosphate compound in the muscle, creatine phosphate (CP), is immediately broken down into phosphate and creatine releases energy for adenosine diphosphate to synthesize adenosine triphosphate. However, creatine phosphate in muscle is also limited and must be continuously synthesized. The energy required for the re-synthesis of creatine phosphate is derived from the decomposition of sugar. The decomposition of sugar depends on the condition of oxygen supply in the body at that time. When oxygen supply is sufficient, it comes directly from the aerobic oxidation of sugar or fat; When oxygen supply is insufficient, it comes from anaerobic glycolysis of sugar, and lactic acid is formed as a result. When the oxygen supply is sufficient, part of the lactic acid continues to oxidize and release energy, but most (4/5) resynthesize liver glycogen.
The energy conversion in the body is very complex, and the energy generated is not all rapidly converted into thermal energy. There are 20 ~ 25% into the mechanical work, a small part of the conversion of electrical energy, most of the heat in the form of emission. However, when the body completes any work, any form of energy is eventually converted to thermal energy. The heat released by the body is the precise scale of the energy consumption of the whole body, so the measurement of the energy released during the thermal reaction is called calorimetry. But the direct measurement of the body's heat is very inconvenient. Later, it was found that there was a precise correlation between the heat released by the body and the amount of carbon dioxide and oxygen consumed. Therefore, in the actual work, it is common to use the gas metabolism method to determine the energy consumption value indirectly. This method, called indirect calorimetry, has the advantages of portable instrument, simple operation and accuracy.
biological activity Adenosine 5 '-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate, it is the product of ATP dephosphorylation by ATPase. Adenosine 5 '-diprospate induces human platelet aggregation and inhibits stimulated adenylate cyclase through action on the p2t-purine receptor.
category toxic substances
toxicity grade poisoning
Acute toxicity intraperitoneal-mouse LD50: 3333 mg/kg
flammability hazard characteristics flammability; Combustion releases toxic oxides of nitrogen and phosphorus fumes
storage and transportation characteristics The warehouse is ventilated and dried at low temperature; Stored separately from food raw materials
extinguishing agent dry powder, foam, sand, carbon dioxide, water mist

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.

 

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