Tolazoline hydrochloride 59-97-2

Details:

Product introduction:

Molar Mass	196.68
Melting Point	172-176 °C
Boling Point	338.2°C at 760 mmHg
Flash Point	158.3°C
Solubility	DMSO (Slightly, Heated), Methanol (Slightly)
Vapor Presure	0.000196mmHg at 25°C
Appearance	Crystalline Powder
Color	White to almost white
Merck	14,9506
Storage Condition	Inert atmosphere,Room Temperature
Stability	Hygroscopic
Sensitive	Hygroscopic
MDL	MFCD00012693
Use	Used as vasodilator
In vitro study	Tolazoline is a pulmonary vasodilator used to attenuate pulmonary vascular resistance (PVR) in neonates with persistent pulmonary hypertension (PPHN). Tolazoline has moderate alpha-adrenergic blocking activity and histamine agonist activity. Tolazoline is commonly used to reduce pulmonary artery pressure and vascular resistance. For all the spasmogenic drugs investigated, Tolazoline did not have a broad range of effects as did SNP. However, in the human radial artery, it may be effective in counteracting alpha-adrenergic receptor-mediated vasospasm.

Content determination

• measured by high performance liquid chromatography (General 0512).
• chromatographic conditions and system suitability test using eighteen alkyl silane bonded silica as filler; Methanol-0.068% phosphoric acid solution [(50:50), the pH value was adjusted to 3.0 with ammonia solution. The detection wavelength was 230nm. The number of theoretical plates shall not be less than 1500 based on the calculation of tazolin peak.
• determination of 20 tablets of this product, precision weighing, fine grinding, precision weighing an appropriate amount (about 50mg equivalent to tolazoline hydrochloride), put in a 100ml measuring flask, add an appropriate amount of mobile phase, ultrasonic dissolution of tolazoline hydrochloride, dilute to scale with mobile phase, shake well, filter, Take 5ml of continued filtrate precisely, put it in 50ml measuring flask, dilute to scale with mobile phase, shake well, accurately measure 20ul, inject human liquid chromatograph, record the chromatogram; Take another reference substance of tolazoline hydrochloride, the mobile phase was added to dissolve and quantitatively dilute to prepare a solution containing about 50ug per 1 ml, which was determined by the same method. According to the external standard method to calculate the peak area, that is.

 

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

 

 

 

 

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1.Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3.How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5.Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6.How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.