Cyclopenta[b]pyridi...

Cyclopenta[b]pyridine    533-37-9
Cyclopenta[b]pyridine    533-37-9
Cyclopenta[b]pyridine    533-37-9
Cyclopenta[b]pyridine    533-37-9
Cyclopenta[b]pyridine    533-37-9

Cyclopenta[b]pyridine 533-37-9

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 1.0000 -10.0000

  • Min.Order :1 Kilogram
  • Purity: >99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

6,7-Dihydro-5H-cyclopenta(b)pyridine 5H-1-Pyrindine,6,7-dihydro- CPP

Quick Details

  • Appearance:Liquid
  • Application:Used as a pharmaceutical intermediate
  • PackAge:In plastic outside weave or according to your request
  • ProductionCapacity:500|Kilogram|Week
  • Storage:Sealed in dry,Room Temperature
  • Transportation:We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.?

Superiority:

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

Introduction

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is an organic compound commonly abbreviated as TMSA. The following is an introduction to its nature, use, preparation and safety information:

Nature:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a colorless liquid with good solubility in water and most organic solvents. Its molecular formula is C9H16O4 and its molecular weight is 188.22g/mol. It has a density of about 0.995 g/mL and a boiling point of about 198-200 ° C.

Use:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a commonly used organic synthesis intermediate. It can be used as a substrate, reducing agent and ligand for chiral catalysts. In addition, it can also be used to prepare organic compounds such as drugs, fragrances and dyes.

Method: The preparation of
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER usually involves specific synthetic routes and chemical reactions. A common synthetic method is to obtain (R)-2-methyl-3-methylthiopropionate by oxidation of methyl propyl mercaptan (MPTS), followed by methyl esterification with acetic anhydride to obtain the desired product. Specific synthesis steps and conditions can be adjusted according to needs and experimental conditions.

Safety Information:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a chemical, so you need to pay attention to safety when using and handling it. It is combustible and should be kept away from fire and flame. Wear protective gloves, goggles and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with water and seek medical assistance. In addition, it should be kept away from children and animals, stored in sealed containers, and placed in a cool, dry place.

Details:

Product Description:

Introduction

Density 1.018 g/mL at 25 °C (lit.)
Melting Point 117 °C
Boling Point 87-88 °C/11 mmHg (lit.)
Flash Point 153°F
Vapor Presure 0mmHg at 25°C
Appearance clear liquid
Color Colorless to Red to Green
pKa 6.19±0.20(Predicted)
Storage Condition Sealed in dry,Room Temperature
Refractive Index n20/D 1.544(lit.)
Physical and Chemical Properties Density 1.018
boiling point 108-110 ° C (66 mmHg)
refractive index 1.544
flash point 67°C
Use Used as a pharmaceutical Intermediate
overview 2,3-cyclopentenopyridine is a pyridine derivative, an important intermediate for the synthesis of cefpirome, and is also widely used in the preparation of plant protectants, synthetic resins, plastic products, etc. Cefpirome, as the fourth generation of new cephalosporins, has the characteristics of broad spectrum, high efficiency, low toxicity and enzyme resistance. Cefpirome is the antibiotic with the strongest antibacterial activity against Gram-positive bacteria among the known cephalosporins. It was listed in Sweden as early as 1992 under the trade name of Cefrom. Although cefpirome has been listed and used in developed countries for 20 years, due to the limitations of domestic economy and technology, it has not been able to form a scale and is still in its infancy.
preparation first, 1.6132g of titanium tetrachloride and 19.3g of ethanol are mixed to prepare a titanium-containing impregnating solution, the titanium-containing impregnating solution is added into 20gγ-Al2O3 (pore volume 0.61 ml/g), impregnated for 12h, dried at 80 ℃ for 4h, and then cooled naturally to obtain 2% Ti/γ-Al2O3; the impregnation solution prepared by mixing 2.3351gCu(NO3)2. 3H2O and 12.2g of water is added into 2% Ti/γ-Al2O3, impregnated for 12h, dried at 80 ℃ for 4h, and calcined at 500 ℃ to prepare 3% Cu/2% Ti/γ-Al2O3 modified alumina catalyst. Finally, the modified alumina catalyst was used to synthesize 2,3-cyclopentenopyridine: the raw material glycerin aqueous solution (mass concentration is 15%), cyclopentanone, ammonia and carrier gas nitrogen are introduced into a fixed bed reactor equipped with modified alumina catalyst 3% Cu/2%Ti/γ-Al2O3. The hourly space velocity of the feed liquid of the glycerin aqueous solution is 0.23 h-1, the hourly space velocity of the feed liquid of cyclopentanone is 0.07 h-1, the ammonia gas h-1 is 54.0, and the nitrogen gas space velocity is 1066.3 h-1. When the reaction is carried out at normal pressure and 300 ℃, the conversion of glycerol was 70.3%, and the selectivity of 2, 3-cyclopentenopyridine was 81.6%.

using the process conditions of this embodiment, the reaction raw material glycerin is cheap and easy to obtain, not only industrial grade pure glycerin, but also crude glycerin produced by biodiesel can be used, which solves the problem of a large amount of excess glycerin produced by biodiesel and ensures the sustainable development of the whole industrial chain. However, the modified alumina catalyst carrier is easy to obtain, the preparation method is simple, the operation is easy, the catalyst activity is high, and the stability is good. The modified alumina catalyst is used in the gas-solid phase reaction of 2, 3-cyclopentenopyridine synthesized from glycerol, cyclopentanone and ammonia as raw materials, and has good results. The catalyst is cheap, the reaction is easy to implement, the reaction conditions are mild, and it has good development prospects.
Use Used as a pharmaceutical intermediate
Used as an intermediate for the drug cefpirome

 

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.

 

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