tert-Butyl 1-piperazinecarboxylate57260-71-6

Details:

57260-71-6 - Names and Identifiers

Name	1-boc-piperazine
Synonyms	piboc 4-Boc-piperazine 1-boc-piperazine n-boc-piperazine 1-n-boc-piperazine n-(t-boc)piperazine rarechem ar pa 0026 1-Boc-piperazine acetate n-t-butoxycarbonylpiperazine N-(tert-Butoxycarbonyl)piperazine N-tert-Butyloxycarbonylpiperazine tert-butyl-piperazine carboxylate 1-(tert-butoxycarbonyl)piperazine n-(tert-butoxycarbonyl)piperazine 1-(tert-Butoxycarbonyl)piperazine Tert-butyl 1-piperazinecarboxylate tert-butyl-1-piperazinecarboxylate 1-(tert-Butyloxycarbonyl)piperazine tert-butyl piperazine-1-carboxylate 4-(tert-Butyloxycarbonyl)piperazine n-(tert-butyloxycarbonyl)-piperazine 4-(tert-butoxycarbonyl)piperazin-1-ium 1,1-Dimethylethyl1-piperazinecarboxylate 1,1-Dimethylethyl piperazin-1-carboxylate 1-[(1,1-Dimethylethoxy)carbonyl]piperazine tert-Butyl piperazine-1-carboxylate acetate 1-Piperazinecarboxylic acid tert-butyl ester piperazine-1-carboxylic acid tert-butyl ester tert-butyl tetrahydropyrazine-1(2h)-carboxylate 2-piperazinecarboxylicacid,1,1-dimethylethylester 1-Piperazinecarboxylicacid, 1,1-dimethylethyl ester 1-Piperazinecarboxylic acid tert-butyl ester ethanedioate
CAS	57260-71-6 146398-94-9
EINECS	611-489-0
InChI	InChI=1/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3/p+1
InChIKey	CWXPZXBSDSIRCS-UHFFFAOYSA-N

57260-71-6 - Physico-chemical Properties

Molecular Formula	C9H18N2O2
Molar Mass	186.25
Density	1.030±0.06 g/cm3(Predicted)
Melting Point	47-49℃
Boling Point	258°C at 760 mmHg
Flash Point	109.8°C
Water Solubility	Soluble in ethyl acetate, methanol and water.
Vapor Presure	0.0141mmHg at 25°C
Appearance	Low Melting Crystalline Mass
Color	White to light yellow
BRN	879985
pKa	8.45±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Sensitive	Air Sensitive
Use	In modern chemical pharmaceuticals, 1-tert-butoxycarbonylpiperazine plays a very important role, because it is an important basic chemical raw material for many antitussive drugs, anti-allergic drugs, antipsychotic drugs, antibacterial drugs, various pesticides, etc. Due to its wide range of uses, increasing demand, accounting for a high proportion of the cost of various drugs, so reducing the industrialization cost of 1-tert-butoxycarbonylpiperazine has very important industrial value and economic value.

57260-71-6 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	3263
WGK Germany	3
FLUKA BRAND F CODES	3-10-34
HS Code	29335995
Hazard Class	IRRITANT

57260-71-6 - Introduction

Use
1-tert-butoxycarbonylpiperazine is a useful organic synthetic compound.

Application
N-Boc-piperazine can be used to prepare the downstream product 1-[5-(trifluoromethyl)-2-pyridyl] piperazine.

Synthesis method
At present, the method of synthesizing 1-tert-butoxycarbonylpiperazine is mainly to use anhydrous piperazine drops and ditert-butyl dicarbonate to selectively react to protect the nitrogen on one end of piperazine, so that the amino group on the other end is removed. In this reaction method, both ends of piperazine will be connected with ditert-butyl dicarbonate, and a large amount of water must be used for purification. Wash.

Use as an organic intermediate

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

Superiority
As a reliable partner for Chinese market, we are specialized in chemical raw materials; consolidate sourcing, marketing, sales, distribution and after-sale services, providing our partners with sourcing evaluation, technology supports, toll/contract manufacture, investment solution and suitable partnership establishment in China.
Service we can provide:
1. provide costomers with "one-stop"packaging service,from manufacture ,research,development,production,export and so on
2. Quality control, before shipment.
3. Prompt shipment with professional documents
4. Packing as your request, with photo before shipment
5.Mix and different products in ONE PCL,increase the working efficiency for customers.
6.We can export from many China main ports,convenient for the customes provide logistics services.
Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1.Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3.How long is lead time  
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located How can I visit the factory   
 Our factory located in HEBEI, China.

5.Can i get some samples 
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6.How to start orders or make payments 
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders 
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

9.How do you treat quality complaint

First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.