Benzamidine,p-amino-, dihydrochloride (6CI,7CI,8CI) Benzenecarboximidamide, 4-amino-,dihydrochloride (9CI) 4-Amidinoaniline dihydrochloride
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4-Aminobenzamidine dihydrochloride Usage And Synthesis |
Chemical Properties | white to yellowish fine crystalline powder |
Uses | 4-Aminobenzamidine dihydrochloride is a synthetic diamidine derivative that acts as a urokinase inhibitor as well as trypsin inhibitor. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes. |
Application | 4-Aminobenzamidine dihydrochloride can be used to synthesize: Orally active fibrinogen receptor antagonists based on benzamidines. Benzamidine derivatives that are selective and potent serine protease inhibitors. Novel pyrrolo [3,2-c] quinolines that are structural analogs of topoisomerase inhibitors such as coralyne and fagaronine. Synthesis of a selective inhibitor of PRMT1 (SKLB-639) |
Preparation | 4-Aminobenzamididine dihydrochloride is obtained by cyanation, addition, amination and reduction of 4-nitrobenzoic acid. |
Definition | ChEBI: P-Aminobenzamidine dihydrochloride is an organic molecular entity. |
4-Aminobenzamidine dihydrochloride Preparation Products And Raw materials |
Raw materials | Ethanol-->Hydrochloric acid-->Methanol-->Sodium-->Acetone-->Palladium-->Ammonium chloride-->Iron-->Sodium Methoxide-->Tin-->Stannous chloride-->4-Nitrobenzoic acid-->Tetrabutylammonium fluoride-->Benzhydrylamine-->Ferrous sulfide-->4-Nitrobenzonitrile-->Benzenecarboximidic acid, 4-nitro-, methyl ester |
Preparation Products | Dabigatran Etexilate iMpurity I |
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