FRAXINELLONE 28808-62-0

Min.Order / FOB Price:Get Latest Price

5 Kilogram	FOB Price:USD 45.0000 -65.0000

5 Kilogram

FOB Price:USD 45.0000 -65.0000

Min.Order :5 Kilogram
Purity: >99%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

1(3H)-Isobenzofuranone,3-(3-furanyl)-3a,4,5,6-tetrahydro-3a,7-dimethyl-, (3R-cis)- Fraxinellone Phthalide,3-(3-furyl)-3a,4,5,6-tetrahydro-3a,7-dimethyl- (8CI)

Quick Details

Appearance:White Crystalline Powder
Application:Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). Cytosine reagent is used in a wide variety of research applications, as an
PackAge:Brown vial or HDPE plastic bottle
ProductionCapacity:3000|Kilogram|Month
Storage:Cool Dry Place
Transportation:Bag or Drum

Superiority:

OEM Supply Superior Quality 99% Cytosine CAS 71-30-7

Basic Information:

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.

Product Name:	Cytosine
Synonyms:	4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE
CAS:	71-30-7
MF:	C4H5N3O
MW:	111.1

Details:


Molecular Formula	C14H16O3
Molar Mass	232.27
Density	1.1649 (rough estimate)
Melting Point	114.0 to 118.0 °C
Boling Point	314.44°C (rough estimate)
Specific Rotation(α)	(EtOH)-44
Flash Point	179.3°C
Solubility	Easily soluble in chloroform and ethyl acetate.
Vapor Presure	9.29E-06mmHg at 25°C
Appearance	Colorless needle crystal
Storage Condition	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Refractive Index	1.5557 (estimate)
MDL	MFCD11101451
Physical and Chemical Properties	化学性质白色结晶粉末，易溶于氯仿、乙酸乙酯，来源于白鲜皮，白柳(Salix alba L.)的皮。
Use	Uses tryptanthrin is an insecticide that inhibits larval growth and is used for the treatment and protection of crops and agricultural products. Also, it is a natural compound that can be used to treat tumors.
In vitro study	Fraxinellone (0-100 μM；12 hours) decreases the percent of PD-L1 positive cells from 20.4% to 11.4% in A549 cells. Cell Viability Assay Cell Line: A549 cells Concentration: 0 μM, 10 μM, 30 μM, 100 μM Incubation Time: 12 hours Result: Inhibited the percent of PD-L1 positive cells.
In vivo study	Fraxinellone (oral gavage; 30 and 100 mg/kg; every three days; 30 days) significantly suppresses tumor growth, reduces HIF-1α, pTyr705 STAT3, PD-L1 and VEGF staining compared with the control group in female athymic BALB/c nude mice. Animal Model: BALB/c nude mice Dosage: 30 and 100 mg/kg Administration: Oral gavage; 30 and 100 mg/kg; every three days; 30 days Result: Significantly suppressed tumor growth.