Tussilagone 104012-37-5

Min.Order / FOB Price:Get Latest Price

5 Kilogram	FOB Price:USD 45.0000 -65.0000

5 Kilogram

FOB Price:USD 45.0000 -65.0000

Min.Order :5 Kilogram
Purity: >99%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

2-Pentenoicacid, 3-methyl-,1-[1-(acetyloxy)ethyl]octahydro-4-methylene-7-(1-methylethyl)-2-oxo-1H-inden-5-ylester, [1S-[1a(S*),3ab,5b(E),7a,7aa]]- Tussilagone L 652469

Quick Details

Appearance:White rystalline Powder
Application:Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). Cytosine reagent is used in a wide variety of research applications, as an
PackAge:Brown vial or HDPE plastic bottle
ProductionCapacity:3000|Kilogram|Month
Storage:Cool Dry Place
Transportation:Bag or Drum

Superiority:

OEM Supply Superior Quality 99% Cytosine CAS 71-30-7

Basic Information:

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.

Product Name:	Cytosine
Synonyms:	4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE
CAS:	71-30-7
MF:	C4H5N3O
MW:	111.1

Details:

Molecular Formula	C23H34O5
Molar Mass	390.51
Density	1.07±0.1 g/cm3 (20 ºC 760 Torr)
Boling Point	471.3±35.0 °C(Predicted)
Specific Rotation(α)	-40 (c, 1 in CHCl3)
Solubility	Soluble in chloroform and methanol, hardly soluble in water
Appearance	White powder or crystal
Storage Condition	2-8℃
MDL	MFCD01709134
Physical and Chemical Properties	White crystalline powder, soluble in ether, chloroform, ethyl acetate, methanol, insoluble in water, derived from the flower buds of the farfara of the Tussilago of the Compositae family, Senrito Senecio kleinia Less root.
In vitro study	Tussilagone suppressed the expression of the inflammatory mediators, nitric oxide and prostaglandin E2, and the inflammatory cytokines, tumor necrosis factor-alpha (TNF-α) and high-mobility group box 1 (HMGB1), in lipopolysaccharide-stimulated RAW 264.7 cells and peritoneal macrophages. Tussilagone also reduced the activation of the mitogen-activated protein kinases and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) involved in the activation of various inflammatory mediators in activated macrophages.
In vivo study	Tussilagone administration (1 mg/kg and 10 mg/kg) produced decreased mortality and lung injury in CLP-activated septic mice. Augmented expression of cyclooxygenase (COX)-2 and TNF-α in pulmonary alveolar macrophages of septic mice were attenuated by tussilagone administration.