5-Methyl-1-phenyl-1H-pyridin-2-one 5-Methyl-1-phenyl-2(1H)-pyridinone 5-Methyl-1-phenyl-2(1H)-pyridone
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Common name: Pirfenidone
Category:Pharmaceutical raw material
Other name: 5-Methyl-1-phenylpyridine-2(1H)-one
CAS No.: 53179-13-8
EINECS No.: 621-260-7
Appearance: Solid
Molecular formula: C12H11NO
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
Molecular Weight |
185.22 |
Boiling point |
329.1±15.0 °C(Predicted) |
Melting point |
96-97°C |
Density |
1.137±0.06 g/cm3(Predicted) |
Purity |
≥99.0% |
PH |
/ |
Soluble |
DMSO: soluble ≥10 mg/mL |
Water solubility |
Soluble to 20 mm in water |
Color |
White |
Product Description:
Pirfenidone is a small - molecule oral drug with significant therapeutic value. Chemically, it is 5 - methyl - 1 - phenyl - 2 - (1H) - pyridone, featuring a unique structure that enables it to exert multiple pharmacological effects. This drug is primarily recognized for its potent anti - fibrotic properties. It works by inhibiting the production of various pro - fibrotic cytokines, such as transforming growth factor - beta (TGF - β), which are responsible for the excessive deposition of extracellular matrix in fibrotic tissues. In the medical field, pirfenidone has become a cornerstone in the treatment of idiopathic pulmonary fibrosis (IPF). By slowing down the progression of fibrosis in the lungs, it helps patients with IPF to maintain better lung function and quality of life. It is also being investigated for its potential in treating other fibrotic diseases, like liver fibrosis. Our high - quality pirfenidone product is manufactured under strict GMP (Good Manufacturing Practice) standards, ensuring consistent purity, stability, and bioavailability, making it a reliable choice for pharmaceutical companies, research institutions, and patients in need of effective anti - fibrotic treatment.
Application:
Pirfenidone is mainly used in treating idiopathic pulmonary fibrosis (IPF). By curbing the over - production of fibrotic factors in the lungs, it slows down lung tissue scarring, thus improving patients' breathing capacity and quality of life. Additionally, it shows potential in treating other fibrotic conditions such as liver fibrosis, and is often used in research to explore its wider therapeutic applications in various fibrotic diseases.
Package: 25kg/drum or bag
Storage: Sealed in dry, Room Temperature
Executive Standards: International Standard.
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