Unii-qhk6Z47gtg

Unii-qhk6Z47gtg

Unii-qhk6Z47gtg

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : T/T

Keywords

TB500 885340-08-9 UNII-QHK6Z47GTG

Quick Details

  • Appearance:White to Off-White solid
  • Application: facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration.
  • PackAge:According to the need to packing
  • ProductionCapacity:1|Kilogram|Month
  • Storage:-20℃
  • Transportation:air,sea and courier

Superiority:

TB500 Chemical Properties
Boiling point     1405.0±65.0 °C(Predicted)
density     1.281±0.06 g/cm3(Predicted)
solubility     Methanol (Slightly), Water (Slightly)
pka    3.20±0.10(Predicted)
form     Solid
color     White to Off-White
InChIKey    ADKDNDYYIZUVCZ-HLXZCORBNA-N
Safety Information
MSDS Information
TB500 Usage And Synthesis
Description    TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. It acts on the muscular system and has anabolic properties. TB 500 is used primarily for race animals (horses and dogs).
Uses    TB 500 is a peptide hormone that represent an emerging class of potential doping agents.
Biological Activity    TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
Mechanism of action    Blood vessels are an essential precondition for any biochemical activity, including cell proliferation, tissue repair and remodeling, and other activities. In animal and in vitro models, it has been purported that TB-500 may promote the migration of endothelial cells, which line blood vessels. Through its potential to stimulate migration, TB-500 may have the prospect of stimulating the formation of blood vessels in animal models, even in tissues such as cartilage. Findings imply that by promoting cell development, TB-500 may assist in tissue repair and help guarantee that the repair is more comprehensive. It was speculated via research conducted on mice models of heart attack that TB-500 might stimulate the creation of capillary tubes, promoting heart muscle regeneration and preventing heart cell death after damage. In a nutshell, TB-500 may both discourage cell harm and promote cell healing once it has already occurred.
Regulatory Status    In 2011, a veterinary preparation called TB-500 containing the synthetic version of this naturally occurring peptide segment was marketed for equine or greyhound use. Although the preparation is declared '100% drug-free' and 'does not swab', TB-500 (N-acetylated LKKTETQ) is prohibited in horse racing as implicit in Clause 10 of Article 6 of the International Agreement on Breeding, Racing and Wagering (published by the International Federation of Horseracing Authorities)[1].
References    [1] Emmie N M Ho. “Doping control analysis of TB-500, a synthetic version of an active region of thymosin β?, in equine urine and plasma by liquid chromatography-mass spectrometry.” Journal of Chromatography A 1265 (2012): 57–69.

Details:

TB500 Chemical Properties
Boiling point     1405.0±65.0 °C(Predicted)
density     1.281±0.06 g/cm3(Predicted)
solubility     Methanol (Slightly), Water (Slightly)
pka    3.20±0.10(Predicted)
form     Solid
color     White to Off-White
InChIKey    ADKDNDYYIZUVCZ-HLXZCORBNA-N
Safety Information
MSDS Information
TB500 Usage And Synthesis
Description    TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. It acts on the muscular system and has anabolic properties. TB 500 is used primarily for race animals (horses and dogs).
Uses    TB 500 is a peptide hormone that represent an emerging class of potential doping agents.
Biological Activity    TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
Mechanism of action    Blood vessels are an essential precondition for any biochemical activity, including cell proliferation, tissue repair and remodeling, and other activities. In animal and in vitro models, it has been purported that TB-500 may promote the migration of endothelial cells, which line blood vessels. Through its potential to stimulate migration, TB-500 may have the prospect of stimulating the formation of blood vessels in animal models, even in tissues such as cartilage. Findings imply that by promoting cell development, TB-500 may assist in tissue repair and help guarantee that the repair is more comprehensive. It was speculated via research conducted on mice models of heart attack that TB-500 might stimulate the creation of capillary tubes, promoting heart muscle regeneration and preventing heart cell death after damage. In a nutshell, TB-500 may both discourage cell harm and promote cell healing once it has already occurred.
Regulatory Status    In 2011, a veterinary preparation called TB-500 containing the synthetic version of this naturally occurring peptide segment was marketed for equine or greyhound use. Although the preparation is declared '100% drug-free' and 'does not swab', TB-500 (N-acetylated LKKTETQ) is prohibited in horse racing as implicit in Clause 10 of Article 6 of the International Agreement on Breeding, Racing and Wagering (published by the International Federation of Horseracing Authorities)[1].
References    [1] Emmie N M Ho. “Doping control analysis of TB-500, a synthetic version of an active region of thymosin β?, in equine urine and plasma by liquid chromatography-mass spectrometry.” Journal of Chromatography A 1265 (2012): 57–69.

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