BOC-PYR-OET

Details:

Common name: BOC-PYR-OET

Category:BOC amino acid

Other name: (2S)-5-oxo-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) 2-ethyl ester

CAS No.: 144978-12-1

EINECS No.: 604-450-4

Appearance: Powder

Molecular formula: C12H19NO5

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight	257.28
Boiling point	375.0±35.0 °C(Predicted)
Melting point	52.0 to 56.0 °C
Density	1.182±0.06 g/cm3(Predicted)
Purity	≥99.0%
PH	/
Acidity coefficient (pKa)	-4.15±0.40(Predicted)
Soluble	Freely soluble in methanol
Water solubility	/
Color	White

 

 

Product Description:
BOC - PYR - OET, which is Boc - L - Pyroglutamic acid ethyl ester, typically presents as a white to off - white crystalline solid. Its chemical structure features an L - pyroglutamic acid unit. The amino group is protected by a tert - butoxycarbonyl (BOC) group, and the carboxyl group is esterified with an ethyl group. This configuration endows it with special chemical characteristics. The BOC group effectively shields the amino group from undesired reactions during chemical operations and can be detached under proper acidic circumstances. The ethyl ester group not only enhances the compound's reactivity but also affects its solubility behavior. It has low solubility in water while being highly soluble in common organic solvents like ethanol, chloroform, and acetone. In peptide synthesis and pharmaceutical research, BOC - PYR - OET serves as a vital intermediate. It is extensively applied in the synthesis of peptides, especially those containing pyroglutamic acid residues. By engaging in coupling reactions with other amino acid derivatives, it facilitates the precise construction of intricate peptide chains, playing a key role in peptide bond formation. Additionally, its presence in peptide synthesis can greatly impact the properties of the resulting peptides, including stability, solubility, and biological activity. To maintain its quality and reactivity, it should be stored in a cool, dry place, protected from light and humidity.

 

Application: 

Used for the synthesis of various pharmacological compounds. It is used in the synthesis of hepatitis C proenzyme inhibitors and alkyl renin inhibitors.

Package: 25kg/drum or bag

Storage: Keep in dark place, Sealed in dry, Room Temperature

Executive Standards: International Standard.