7-METHOXYCOUMARIN-3-CARBOXYLIC ACID

Details:

Common name: 7-Methoxycoumarin-3-carboxylic acid

Category:PROTAC functional molecule

Other name: 7-METHOXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID

CAS No.: 20300-59-8

EINECS No.: /

Appearance: Powder

Molecular formula: C11H8O5

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight	220.18
Boiling point	424.4±45.0 °C(Predicted)
Melting point	194 °C
Density	1.454±0.06 g/cm3(Predicted)
Purity	≥99.0%
PH	/
Acidity coefficient (pKa)	1.92±0.20, most acidic, temperature: 25 °C
Soluble	/
Water solubility	/
Color	White

 

 

Product Description:
7 - Methoxycoumarin - 3 - carboxylic acid typically presents as a light - colored crystalline powder, often ranging from white to pale yellow. Structurally, it consists of a coumarin core, which is a fused - ring system composed of a benzene ring and a pyrone ring. The 7 - methoxy group is attached to the benzene ring, adding a methoxy functional group that influences the compound's physical and chemical properties. The 3 - carboxylic acid group on the pyrone ring endows the molecule with acidic properties and provides a reactive site for various chemical reactions.

In terms of solubility, it has limited solubility in water due to the relatively hydrophobic nature of the coumarin backbone. However, it shows better solubility in polar organic solvents such as ethanol, methanol, and N,N - dimethylformamide (DMF). In chemical reactions, the carboxylic acid group can participate in esterification reactions with alcohols to form esters, and it can also react with bases to form salts. The coumarin ring system itself can undergo photochemical reactions, making it sensitive to light.

In the fields of fluorescence research, medicinal chemistry, and materials science, 7 - Methoxycoumarin - 3 - carboxylic acid has significant applications. In fluorescence research, it is often used as a fluorescent probe due to the fluorescence - emitting properties of the coumarin moiety. In medicinal chemistry, it can serve as a building block for the synthesis of potential drug candidates, as its structure can be modified to target specific biological pathways. In materials science, derivatives of this compound can be used to prepare functional materials with unique optical properties. To maintain its quality and stability, it should be stored in a cool, dry place, protected from light and heat sources.

 

Application: 

7 - Methoxycoumarin - 3 - carboxylic acid is used as a fluorescent probe in fluorescence research. In medicinal chemistry, it serves as a building block for synthesizing potential drug candidates. In materials science, its derivatives are applied to prepare functional materials with unique optical properties.

Package: 25kg/drum or bag

Storage: <0°C

Executive Standards: International Standard.