METHYL (4-CYANOPHENYL)ACETATE

Details:

Common name: METHYL (4-CYANOPHENYL)ACETATE

Category:PROTAC linker

Other name: 4-(piperidin-4-yl)butan-1-ol

CAS No.: 52798-01-3

EINECS No.: /

Appearance: Solid

Molecular formula: C10H9NO2

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight	175.18
Boiling point	289.9±23.0 °C(Predicted)
Melting point	221 °C
Density	1.14±0.1 g/cm3(Predicted)
Purity	≥99.0%
PH	/
Acidity coefficient (pKa)	/
Soluble	/
Water solubility	/
Color	Creamy white

 

 

Product Description:
METHYL (4 - CYANOPHENYL)ACETATE typically appears as a colorless to light - yellow liquid or a white - crystalline solid, depending on environmental conditions and purity. Structurally, it consists of a benzene ring with a cyano group at the para - position and an acetic acid methyl ester moiety attached. The cyano group, with its triple - bonded carbon and nitrogen atoms, imparts unique electronic properties to the molecule. It is highly polar and can participate in various chemical reactions such as nucleophilic addition reactions. The acetic acid methyl ester group at the end of the side - chain provides a site for hydrolysis under acidic or basic conditions, which can lead to the formation of the corresponding carboxylic acid. Also, the ester group can react with other nucleophiles in substitution reactions.

In terms of solubility, it has low solubility in water due to the relatively non - polar nature of the benzene ring and the ester group. However, it shows good solubility in common organic solvents like ethyl acetate, dichloromethane, and chloroform. In chemical reactions, the cyano group can be hydrolyzed to form a carboxamide or a carboxylic acid under appropriate conditions. The ester group can also be involved in trans - esterification reactions with different alcohols to introduce new alkyl groups.

In the fields of organic synthesis and pharmaceutical research, METHYL (4 - CYANOPHENYL)ACETATE is of great significance. In organic synthesis, it serves as a crucial intermediate for constructing more complex organic molecules. For example, the cyano group and the ester group can be used in sequence to build multi - functional compounds. In pharmaceutical research, it can be a starting material for the synthesis of drugs that target specific biological pathways. Modifying the substituents on the benzene ring or the functional groups attached to it can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry environment, away from moisture, heat, and strong oxidizing agents.

 

Application: 

In organic synthesis, METHYL (4 - CYANOPHENYL)ACETATE is a crucial intermediate for constructing complex organic molecules, used to build multi - functional compounds through reactions of its cyano and ester groups. In pharmaceutical research, it serves as a starting material for drugs targeting specific biological pathways, and structure modification may lead to novel bioactive substances.

Package: 25kg/drum or bag

Storage: Sealed in dry, Room Temperature

Executive Standards: International Standard.