- Min.Order :0
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
see 1H-Benzimidazole-7-carboxylic acid,1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol- 3-yl)[1,1'-biphenyl]-4-yl]methyl]-2- ethoxy- TAK 536 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
Quick Details
- Appearance:Powder
- Application:It is an angiotensin II receptor antagonist drug under development for the treatment of hypertension, which is mostly used for the treatment of hypertension, and is the only angiotensin II receptor an
- PackAge:25kg/drum or bag
- ProductionCapacity:||
- Storage:Sealed in dry, 2-8°C
- Transportation:by sea or by air
Superiority:
Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.
Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.
The competitive advantages of Colorcom international as your business partner or supplier:
1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.
Details:
Common name: Azilsartan
Category:APIs
Other name: 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid Azilsartan
CAS No.: 147403-03-0
EINECS No.: 808-058-6
Appearance: Powder
Molecular formula: C25H20N4O5
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
|
Molecular Weight |
456.45 |
|
Boiling point |
/ |
|
Melting point |
188 °C(dec.) |
|
Density |
1.42 |
|
Purity |
≥99.0% |
|
PH |
/ |
|
Acidity coefficient (pKa) |
2.05±0.10(Predicted) |
|
Soluble |
The solubility in DMSO is 15mg/mL (clarified solution). |
|
Water solubility |
/ |
|
Color |
White |
Product Description:
Azilsartan usually exists as a white to off - white crystalline powder. Structurally, it belongs to the class of angiotensin II receptor blockers (ARBs), featuring a complex heterocyclic structure with a tetrazole moiety and other aromatic rings. The tetrazole group plays a crucial role in its binding affinity to the angiotensin II receptor. This unique structure endows Azilsartan with specific pharmacological properties.
In terms of solubility, it has relatively low solubility in water, but shows solubility in some organic solvents like methanol and dimethyl sulfoxide (DMSO). In chemical reactions, although it is relatively stable under normal conditions, it may undergo certain transformations under strong acidic or basic conditions.
Pharmacologically, Azilsartan selectively blocks the binding of angiotensin II to the angiotensin II type 1 (AT1) receptor. By doing so, it inhibits the vasoconstrictor and aldosterone - releasing effects of angiotensin II, leading to vasodilation and a reduction in blood pressure. Clinically, it is widely used in the treatment of hypertension. It helps patients with high blood pressure to control their blood pressure levels effectively, reducing the risk of cardiovascular events associated with hypertension. To maintain its quality and potency, Azilsartan should be stored in a cool, dry environment, away from light, heat, and humidity.
Application:
It is an angiotensin II receptor antagonist drug under development for the treatment of hypertension, which is mostly used for the treatment of hypertension, and is the only angiotensin II receptor antagonist (sartan) drug in the late stage of clinical treatment.
Package: 25kg/drum or bag
Storage: Sealed in dry, 2-8°C
Executive Standards: International Standard.
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