Ataluren (PTC124)

Ataluren (PTC124)

Ataluren (PTC124)

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  • Purity: 99%
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Keywords

Ataluren PTC 124 3-[5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid

Quick Details

  • Appearance:Solid
  • Application:Ataluren is mainly used to treat genetic diseases caused by nonsense mutations, like Duchenne muscular dystrophy. It promotes read - through of premature stop codons during translation, enabling funct
  • PackAge:25kg/drum or bag
  • ProductionCapacity:||
  • Storage:Refrigerator.
  • Transportation:by sea or by air

Superiority:

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.

Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

The competitive advantages of Colorcom international as your business partner or supplier:

1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Details:

Common name: Ataluren

Category:APIs

Other name: 3-[5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid

CAS No.: 775304-57-9

EINECS No.: /

Appearance: Solid

Molecular formula: C15H9FN2O3

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight

284.24

Boiling point

503.7±60.0 °C(Predicted)

Melting point

241 - 242°C

Density

1.379

Purity

≥99.0%

PH

/

Acidity coefficient (pKa)

3.58±0.10(Predicted)

Soluble

Dimethyl sulfoxide

Water solubility

/

Color

White

 

 

Product Description:
Ataluren usually appears as a white to off - white crystalline solid. Structurally, it is a small - molecule compound with a unique chemical structure that contains specific functional groups crucial for its biological activity. These functional groups endow it with the ability to interact with ribosomes in a distinct way.

In terms of solubility, it has limited solubility in water, but shows better solubility in some organic solvents like ethanol and dimethyl sulfoxide (DMSO). Under normal storage conditions, it remains relatively stable chemically, yet it may undergo reactions under extreme acidic or basic conditions.

Pharmacologically, Ataluren is designed to address a particular genetic defect. It works by promoting read - through of premature stop codons during translation, allowing the ribosome to continue protein synthesis. This mechanism holds great promise for treating genetic disorders caused by nonsense mutations. Clinically, it is mainly investigated for the treatment of Duchenne muscular dystrophy (DMD) and other genetic diseases associated with nonsense mutations. By enabling the production of functional proteins, it has the potential to improve the symptoms and quality of life for patients suffering from these conditions. To maintain its quality and efficacy, Ataluren should be stored in a cool, dry environment, away from light, heat, and humidity.

 

Application: 

Ataluren is mainly used to treat genetic diseases caused by nonsense mutations, like Duchenne muscular dystrophy. It promotes read - through of premature stop codons during translation, enabling functional protein production to improve patients' symptoms and quality of life.

Package: 25kg/drum or bag

Storage: Refrigerator.

Executive Standards: International Standard.

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