TAK-438

TAK-438

TAK-438

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  • Min.Order :0
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate fumaric acid 1-[5-(2-Fluorophenyl)-1-(3-pyridylsulfonyl)pyrrol-3-yl]-N-methyl-methanamine

Quick Details

  • Appearance:Solid
  • Application:It is used for the treatment of erosive esophagitis, gastric ulcer and duodenal ulcer.
  • PackAge:25kg/drum or bag
  • ProductionCapacity:||
  • Storage:Store at -20°C
  • Transportation:by sea or by air

Superiority:

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.

Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

The competitive advantages of Colorcom international as your business partner or supplier:

1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Details:

Common name: Vonoprazan fumarate

Category:APIs

Other name: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine

CAS No.: 1260141-27-2

EINECS No.: 250-635-4

Appearance: Solid

Molecular formula: C21H20FN3O6S

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight

461.4634032

Boiling point

/

Melting point

/

Density

/

Purity

≥99.0%

PH

/

Acidity coefficient (pKa)

/

Soluble

Insoluble in water; Insoluble in ethanol; 18.9 mg/mL in DMSO

Water solubility

/

Color

White

 

 

Product Description:
Vonoprazan fumarate typically exists as a white to off - white powder. Structurally, it is a novel potassium - competitive acid blocker (P - CAB). It contains a unique bicyclic structure along with specific functional groups. These groups, especially those related to its acid - blocking mechanism, enable it to interact effectively with the proton - potassium ATPase in the gastric parietal cells. The fumarate salt form not only affects its physical properties but also might play a role in its stability and bioavailability.

In terms of solubility, it has limited solubility in water but is soluble in certain organic solvents like methanol and ethanol. Under normal storage conditions, it remains relatively stable. However, it may degrade under extreme conditions such as exposure to strong acids, bases, or high - humidity environments.

Pharmacologically, Vonoprazan fumarate inhibits gastric acid secretion by blocking the potassium - dependent proton pump in the gastric parietal cells more effectively than traditional proton - pump inhibitors. This action results in a long - lasting reduction in gastric acid production. Clinically, it is mainly used for the treatment of acid - related gastrointestinal disorders, including gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions caused by excessive gastric acid. It provides rapid and long - term relief of symptoms related to these disorders. To maintain its quality and effectiveness, Vonoprazan fumarate should be stored in a cool, dry place, away from light, heat, and moisture.

 

Application: 

It is used for the treatment of erosive esophagitis, gastric ulcer and duodenal ulcer.

Package: 25kg/drum or bag

Storage: Store at -20°C

Executive Standards: International Standard.

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