- Min.Order :0
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxyMethyl)-tetrahydro-2H-pyran-3,4,5-triol Empaglifloin Glyxambi
Quick Details
- Appearance:Solid
- Application:Epalliprazin is indicated for the treatment of adults with diabetes who do not achieve adequate glycemic control with diet combined with exercise to improve glycemic control. It should not be used to
- PackAge:25kg/drum or bag
- ProductionCapacity:||
- Storage:2-8°C
- Transportation:by sea or by air
Superiority:
Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.
Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.
The competitive advantages of Colorcom international as your business partner or supplier:
1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.
Details:
Common name: Empagliflozin
Category:APIs
Other name: Empagliflozin API
CAS No.: 864070-44-0
EINECS No.: 620-176-8
Appearance: Solid
Molecular formula: C23H27ClO7
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
|
Molecular Weight |
450.91 |
|
Boiling point |
665℃ |
|
Melting point |
/ |
|
Density |
1.398 |
|
Purity |
≥99.0% |
|
PH |
/ |
|
Acidity coefficient (pKa) |
13.23±0.70(Predicted) |
|
Soluble |
Insoluble in water; ≥20.75 mg/mL in DMSO; ≥ 7.06mg /mL, ethanol solution, ultrasonic |
|
Water solubility |
/ |
|
Color |
White |
Product Description:
Empagliflozin usually appears as a white to off - white crystalline powder. Structurally, it belongs to the class of sodium - glucose co - transporter 2 (SGLT2) inhibitors. It has a unique chemical structure with specific functional groups that are responsible for its high - affinity binding to the SGLT2 protein. These functional groups allow Empagliflozin to selectively block the SGLT2 - mediated reabsorption of glucose in the kidneys.
In terms of solubility, it has moderate solubility in water and is soluble in common polar organic solvents such as ethanol and methanol. Under normal storage conditions, it is relatively stable. However, it may be sensitive to extreme environmental factors like high humidity, strong oxidizing agents, and high temperatures, which could potentially lead to degradation.
Pharmacologically, Empagliflozin works by inhibiting SGLT2 in the renal proximal tubules. This inhibition prevents the reabsorption of glucose from the tubular lumen back into the bloodstream, promoting urinary glucose excretion. As a result, it effectively reduces blood glucose levels in a glucose - independent manner. Clinically, it is primarily used for the treatment of type 2 diabetes mellitus. It can be used either as monotherapy or in combination with other antidiabetic drugs to better manage blood glucose levels in patients with type 2 diabetes. Moreover, Empagliflozin has also been shown to have additional benefits such as reducing the risk of cardiovascular events, including heart failure and stroke, and providing some renal protection. To maintain its quality and potency, Empagliflozin should be stored in a cool, dry environment, protected from light, heat, and moisture.
Application:
Epalliprazin is indicated for the treatment of adults with diabetes who do not achieve adequate glycemic control with diet combined with exercise to improve glycemic control. It should not be used to treat patients with type 1 diabetes, elevated ketones in the blood or urine (diabetic ketoacidosis), severe kidney damage, end-stage kidney disease, and dialysis.
Package: 25kg/drum or bag
Storage: 2-8°C
Executive Standards: International Standard.
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