Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate

Details:

Common name: Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate

Category:Azilsartan & Candesartan Cilexetil intermediates

Other name: Ethyl 1-((2'-cyanobiphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

CAS No.: 139481-41-7

EINECS No.: 604-136-7

Appearance: Solid

Molecular formula: C26H23N3O3

 

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin: China

 

Product Specification:

Molecular Weight	425.48
Boiling point	637.5±65.0 °C(Predicted)
Melting point	/
Density	1.19
Purity	≥99.0%
PH	/
Acidity coefficient (pKa)	4.20±0.10(Predicted)
Soluble	Soluble in chloroform (a little), DMSO (a little), methanol (a little)
Water solubility	/
Color	White

 

 

Product Description:
Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate commonly appears as a white to light - yellow crystalline solid. Structurally, it features a benzimidazole ring. At the 1 - position, there is a [(2'-cyanobiphenyl - 4 - yl)methyl] group, which consists of a biphenyl structure with a cyano group at the 2' - position, adding to the molecule's lipophilicity and reactivity potential, as the cyano group can engage in nucleophilic addition and condensation reactions. The 2 - ethoxy group at the 2 - position imparts polarity and specific reactivity to the molecule. The 7 - position has an ethyl carboxylate group (-COOC?H?), which is susceptible to hydrolysis under acidic or basic conditions, and can also participate in trans - esterification reactions.

In terms of solubility, it has low solubility in water because of the non - polar nature of the biphenyl and benzimidazole rings. However, it shows good solubility in polar organic solvents like ethanol, acetone, and dichloromethane. Under normal storage conditions, it is relatively stable, but exposure to heat, moisture, strong acids, or bases can cause decomposition or chemical reactions.

In the fields of organic synthesis and pharmaceutical research, this compound is of great importance. In organic synthesis, it serves as a crucial building block for constructing complex molecules. By reacting its multiple functional groups with different reagents, a wide variety of multi - functional compounds can be synthesized. In pharmaceutical research, it may be a potential intermediate for the synthesis of drugs with specific biological activities. Modifying the substituents on the benzimidazole or biphenyl rings can potentially lead to the discovery of novel bioactive substances. To maintain its quality and reactivity, it should be stored in a cool, dry place, away from light, heat, moisture, and strong oxidizing or reducing agents.

 

Application: 

It is an intermediate of the herbicide dichloroquinolinic acid.

Package: 25kg/drum or bag

Storage: Sealed in dry,Room Temperature

Executive Standards: International Standard.