KAHWEOL 6894-43-5

Min.Order / FOB Price:Get Latest Price

5 Kilogram	FOB Price:USD 45.0000 -65.0000

5 Kilogram

FOB Price:USD 45.0000 -65.0000

Min.Order :5 Kilogram
Purity: >99%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

Kahweol Kahweol DISCONTINUED, unstable 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol, 3ba,4,5,6,7,8a,9,10,10a,10b-decahydro-7-hydroxy-10bb-methyl- (7CI,8CI)

Quick Details

Appearance:White solid
Application:Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). Cytosine reagent is used in a wide variety of research applications, as an
PackAge:Brown vial or HDPE plastic bottle
ProductionCapacity:3000|Kilogram|Month
Storage:Cool Dry Place
Transportation:Bag or Drum

Superiority:

OEM Supply Superior Quality 99% Cytosine CAS 71-30-7

Basic Information:

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.

Product Name:	Cytosine
Synonyms:	4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE
CAS:	71-30-7
MF:	C4H5N3O
MW:	111.1

Details:

Molecular Formula	C20H26O3
Molar Mass	314.42
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	88-90℃
Boling Point	476.6±45.0 °C(Predicted)
Appearance	White solid
pKa	14.43±0.40(Predicted)
Storage Condition	−20°C
In vitro study	Kahweol (20-40 μM; 24 hours) decreases TGF-β-induced CTGF protein expression in AML12 and LX2 cells. Kahweol (20-40 μM; 1 hour) decreases TGF-β-induced phospho-Smad2/3 expression in AML12 cells, but does not affect expression in LX2 cells. Kahweol (20-40 μM) significantly decreased TGF-β-stimulated phospho-ERK and JNK expression in primary hepatocytes only. kahweol (0-25 μg/ml; 6-24 hours) increased the phosphorylation of AMPK and its downstream target Acetyl-CoA carboxylase (ACC) in a time-dependent manner in 3T3-L1 cells. kahweol (0-25 μg/ml) significantly affects protein expression of PPARγ, C/EBPα, FABP4, and FASN, that regulate adipocyte differentiation and lipid metabolism. Western Blot Analysis Cell Line: 3T3-L1 cells Concentration: 0, 5, 10, 25 μg/ml Incubation Time: Result: Reduced PPARγ, C/EBPα, FABP4, and FASN expression in a dose-dependent manner.