Atovaquone 9...

Atovaquone        95233-18-4
Atovaquone        95233-18-4
Atovaquone        95233-18-4
Atovaquone        95233-18-4
Atovaquone        95233-18-4

Atovaquone 95233-18-4

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 15.0000 -50.0000

  • Min.Order :1 Kilogram
  • Purity: >99%
  • Payment Terms : L/C,D/A,D/P,T/T

Keywords

1,4-Naphthalenedione,2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-, trans- Acuvel Atavaquone

Quick Details

  • Appearance:powder
  • Application:Used as an intermediate in the drug telmisartan
  • PackAge:5mg/vial, 10 vials per box
  • ProductionCapacity:3000|Kilogram|Month
  • Storage:2-8°C
  • Transportation:EMS,DHL,?TNT,?UPS?,FEDEX,?BY?AIR,?BY?SEA DHL?Express,?FedEx?and?EMS?for?quantity?less?than?50KG,?usually?called?as?DDU?service;? Sea?shipping?for?quantity?over?500KG;?And?air?shipping?is?available

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Details:

Molecular Formula C22H19ClO3
Molar Mass 366.84
Density 1.349±0.06 g/cm3(Predicted)
Melting Point 216-2190C
Boling Point 535.0±50.0 °C(Predicted)
Flash Point 277.348°C
Solubility DMSO: >10mg/mL
Vapor Presure 0mmHg at 25°C
Appearance powder
Color yellow
Maximum wavelength(λmax) ['494nm(aq. Buffer)(lit.)']
Merck 14,866
pKa 5.01±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index 1.653
Physical and Chemical Properties Crystallized from acetonitrile, melting point 216-219 ℃.
Use This product is for scientific research only and shall not be used for other purposes.
In vitro study Atovaquone (atavaquone) is a naphthalene compound. Atovaquone is hydroxy-1, 4-naphthoquinone, a ubiquinone analog, which has activity against Pneumocystis. Atovaquone is an antigenic insect mitochondrial electron transfer inhibitor, an antimalarial agent, an anti-Pneumocystis, and is also used in the treatment of toxoplasmosis. It works by interacting with Rieske iron-sulfur proteins and cytochrome B in the ubiquinone oxidation pocket, inhibiting the cytochrome bc(1) complex.
In vivo study Atovaquone is a unique naphthoquinone with a broad spectrum of antiprotozoal activity. It is effective for the treatment and prevention of Pneumocystis carinii pneumonia (PCP), it is effective for the treatment and prevention of malaria in combination with proguanil, and it is effective for the treatment of babesiosis in combination with azithromycin.

 

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