Dydrogesterone 152-62-5

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 15.0000 -50.0000

1 Kilogram

FOB Price:USD 15.0000 -50.0000

Min.Order :1 Kilogram
Purity: >99%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

9b,10a-Pregna-4,6-diene-3,20-dione(6CI,8CI) Dydrogesterone 6-Dehydro-9b,10a-progesterone

Quick Details

Appearance:neat
Application:Used as an intermediate in the drug telmisartan
PackAge:5mg/vial, 10 vials per box
ProductionCapacity:3000|Kilogram|Month
Storage:2-8°C
Transportation:EMS,DHL,?TNT,?UPS?,FEDEX,?BY?AIR,?BY?SEA DHL?Express,?FedEx?and?EMS?for?quantity?less?than?50KG,?usually?called?as?DDU?service;? Sea?shipping?for?quantity?over?500KG;?And?air?shipping?is?available

Superiority:

Our Advantage

Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.

Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.

24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.

High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.

Details:

Molecular Formula	C21H28O2
Molar Mass	312.45
Density	1.0697 (rough estimate)
Melting Point	168-173°C
Boling Point	392.36°C (rough estimate)
Specific Rotation(α)	D25 -484.5° (chloroform)
Flash Point	172.2°C
Solubility	DMSO : 33.33 mg/mL (106.67 mM; Need ultrasonic)
Vapor Presure	9.55E-09mmHg at 25°C
Appearance	neat
Color	White to Light Yellow
Storage Condition	2-8°C
Refractive Index	1.4900 (estimate)
In vitro study	Dydrogesterone acts on endothelial cells alone or in combination with estrogens, producing a neutral effect on NO synthesis and on the activity and expression of eNOS.
In vivo study	Dydrogesterone abolished the stress-induced increase in miscarriage rate in mice. Dydrogesterone brought the percentage of CD8 uterine cells back to the level of control mice. Dydrogesterone significantly reduced the relative number of mouse TNF-α-producing uterine cells after 7.5,9.5, and even 10.5 days in mice. When Dydrogesterone acted on stressed mice, the percentage of uterine cells IL-4 pregnancy protection increased 7.5 days after the start of pregnancy, and even more significantly, and this increase continued until day 10.5. Dydrogesterone abolished the elevated rate of miscarriage in mice subjected to sound stress. Dydrogesterone acts on stressed mice and increases plasma PIBF levels, but does not affect progesterone levels. Dydrogesterone significantly increased the percentage of IL-4-positive decidual immune cells in stressed mice.