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ALPHA-DELTA-UA-[1->3]-GLCNAC SODIUM SALT DELTA-DIHA SODIUM SALT HYALURONIC ACID DISACCHARIDE SODIUM SALT
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Unsaturated hyaluronic acid biose refers to a specific disaccharide unit derived from hyaluronic acid (HA), a natural polysaccharide critical in connective tissues, skin, and synovial fluid. Here's a concise breakdown:
Structure:
Composed of two linked sugars:D-glucuronic acid (with a 4,5-unsaturated double bond, denoted as Δ4,5-GlcA)
N-acetyl-D-glucosamine (GlcNAc)
Bonded via a β-1,3 glycosidic linkage.
Formation:
Generated during enzymatic degradation (e.g., by hyaluronidase) of hyaluronic acid. The enzyme cleaves HA chains, creating unsaturated bonds at the cleavage site.Significance:
Acts as a biomarker for HA turnover in tissues.
Used in research to study HA metabolism, inflammation, and tissue remodeling.
Potential applications in drug delivery or regenerative medicine due to its small size and bioactive properties.
Key Feature:
The unsaturated double bond enhances reactivity, enabling detection via UV absorbance (232 nm) or mass spectrometry.This disaccharide is a fundamental unit for understanding HA breakdown and its role in health and disease.
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