3-BROMO-5-FLUORO-2-METHOXYPYRIDINE 3-Bromo-5-fluoro-2-methoxypyridine ,98% Pyridine, 3-bromo-5-fluoro-2-methoxy-
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3-Bromo-5-fluoro-2-methoxypyridine (corrected from "pyrdine") is a substituted pyridine derivative with the following structure:
Core: Pyridine ring (a 6-membered aromatic ring with one nitrogen atom).
Substituents:
Bromine (Br) at position 3 (meta to the nitrogen).
Fluorine (F) at position 5 (para to the nitrogen).
Methoxy (-OCH?) at position 2 (ortho to the nitrogen).
Molecular Formula: C?H?BrFNO.
Molecular Weight: ~220.01 g/mol.
Appearance: Likely a white to off-white crystalline solid.
Applications:
Pharmaceutical Intermediate: Used in drug discovery, particularly in synthesizing bioactive molecules (e.g., kinase inhibitors).
Agrochemicals: May act as a building block for pesticides or herbicides.
Material Science: Potential use in ligands for catalysis.
Typically prepared via:
Halogenation (bromination/fluorination) of a pre-functionalized pyridine.
Methoxy group introduction via nucleophilic substitution (e.g., using methylating agents like CH?I).
May be irritant (due to bromine/fluorine).
Handle with gloves/eye protection in a fume hood.
This compound’s halogen and methoxy groups enhance reactivity for cross-coupling reactions (e.g., Suzuki-Miyaura), making it valuable in organic synthesis.
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