CasNo.84605-04-9,N-nitroso-N-methyltyramine;84605-04-9,(84605-04-9) Suppliers

10 Milligram	FOB Price: USD 10.0000

Min.Order :10 Milligram
Purity: 99%+ HPLC
Payment Terms : T/T

Keywords

N-nitroso-N-methyltyramine 84605-04-9 C9H12N2O2

Quick Details

Appearance:White to off white powder
Application:experiment research
PackAge:Food bags, aluminum foil bags
ProductionCapacity:5000|Gram|Year
Storage:cool and dry
Transportation:DHL,EMS,TNT,UPS,EMS,by air,by sea;

Superiority:

We supply over 20000 types of spot impurity reference materials, with sufficient supply and same day delivery to meet customers' urgent needs for replenishment at any time. The company has its own research and development center and laboratory, and the team members have over ten years of experience in developing drug impurity reference standards. Our website www.molcoo.com covers over 98% of cutting-edge generic drug projects, with complete structural formulas that greatly save customers time in impurity structure analysis and inference. All products undergo strict quality control testing and provide relevant information such as COA, H-NMR, C-NMR, MS/GC-MS, HPLC/GC purity, QNMR quantification, TGA thermogravimetric analysis, IR infrared, UV ultraviolet, two-dimensional (COSY, NOESY, HMBC, HMQC), etc. These structural confirmation spectra ensure quality and reliability. Our products have a wide range of categories, fast delivery time, good quality, and low prices, which can quickly solve various customer needs such as replenishment and consistency evaluation.

Details:

WhatsAPP: +86 17320513646 E-mail: anna@molcoo.com

Product Information (N031287)

Product Code：N031287
English Name：N-(4-Hydroxyphenethyl)-N-methylnitrous Amide
English Alias：N-(4-hydroxyphenethyl)-N-methylnitrous amide
CAS No.：84605-04-9
Molecular Formula：CHNO
Molecular Weight：180.20

Advantages

High-Purity Reference Standard：Confirmed by HPLC (≥99.0%), NMR, and HRMS, suitable for qualitative/quantitative analysis of nitrosamine impurities.
Controllable Stability：Stable for 24 months at -20℃ under light-protected, sealed storage; degradation rate <0.3% in methanol solution within 1 month.

Applications

Drug Safety Testing：Used for LC-MS/MS detection of N-nitroso impurities in related drugs, complying with ICH M7 guidelines for genotoxic impurities.
Process Optimization：Monitors nitrosation side reactions during drug synthesis to reduce impurity formation via condition adjustment.

Background Description

This compound belongs to nitrosamines, potentially formed by reactions between amines and nitrosating agents during drug synthesis or storage. Nitrosamines pose genotoxic risks, and regulatory agencies (FDA, EMA) enforce strict limits, making research on such impurities crucial for drug quality control.

Research Status

Current research focuses on developing detection methods (e.g., UPLC-MS/MS) and analyzing formation mechanisms of nitrosamine impurities. Studies show that process optimization or inhibitor addition can reduce their content, with toxicology indicating potential mutagenicity requiring limits below 0.1 ppm.

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com

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