Octreotide acetate Somatostatin analogues 83150-76-9
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Octreotide acetate is an artificially synthesized octapeptide with pharmacological effects similar to those of the natural hormone somatostatin. It is a long-acting somatostatin analogue that can bind to somatostatin receptors in the central nervous system, pituitary gland and pancreatic β cells, etc., to produce biological effects.
Octreotide acetate is mainly used to treat acromegaly, controlling symptoms by reducing the plasma concentrations of growth hormone (GH) and auxin mediator C. In addition, it is also applicable to alleviating the symptoms related to gastrointestinal, pancreatic and endocrine tumors
This product has inhibitory effects on the following conditions:
The release of growth hormone (GH) caused by arginine, exercise and insulin-induced hypoglycemia stimulation.
The secretion of insulin, glucagon, gastrin, and other peptides in the gastroenteropancreatic system after meals, as well as the secretion of insulin and glucagon caused by arginine.
The release of thyroid stimulating hormone (TRH) caused by the stimulation of TRH. In patients with acromegaly, this product can reduce the plasma concentration of GH and/or auxin mediator C.
This product can significantly alleviate the clinical symptoms of most patients, such as headache, thickened skin, soft tissue swelling, excessive sweating, joint pain and abnormal sensations, etc. In addition, this product can reduce the size of certain large pituitary adenomas. In patients with gastrointestinal, pancreatic and endocrine system tumors, this product can improve the clinical condition and alleviate various clinical symptoms.
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