CasNo.77086-21-6,Dizocilpine 77086-21-6,(77086-21-6) Suppliers

1 Kilogram	FOB Price:USD 48.0000 -58.0000

Min.Order :1 Kilogram
Purity: ≧ 99%
Payment Terms : D/A,D/P,T/T,Other

Keywords

Dizocilpine 10,11-dihydro-5-methyl-, (5S,10R)- 5H-Dibenzo[a,d]cyclohepten-5

Quick Details

Appearance:powder
Application:An effective anticonvulsant, it is a selective non-competitive NMDA receptor antagonist
PackAge:In plastic outside weave or according to your request
ProductionCapacity:200 tons|Metric Ton|Week
Storage:-20°C
Transportation:according to your request

Superiority:

Our advantages:

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

Details:

Molecular Formula	C16H15N
Molar Mass	221.3
Density	1.144±0.06 g/cm3(Predicted)
Melting Point	68.5-69°
Boling Point	320.3±11.0 °C(Predicted)
Specific Rotation(α)	20589 +161.4° (c = 0.038 g/2 ml ethanol)
pKa	7.96±0.40(Predicted)
Storage Condition	-20℃
In vitro study	Dizocilpine (MK-801) progressively suppresses of current induced by NMDA. Mg 2+ (10 mM) prevents Dizocilpine from blocking the N-Me-D-Asp-induced current, even when Dizocilpine is applied for a long time in the presence of NMDA. Dizocilpine blocks NMDA-activated single-channel activity in outside-out patches. Dizocilpine (MK-801; <500 μM) inhibits activation of microglia induced by LPS with increased Cox-2 protein expression in BV-2 cells. Dizocilpine (<500 μM) reduces microglial TNF-α output with an EC 50 of 400 μM in BV-2 cells.
In vivo study	Dizocilpine (MK 801) (1 mg/kg) treatment before each METH injection reduces the extent of DA depletion by 55% in striatal of mice. Dizocilpine (MK 801) (1 mg/kg) also attenuates the effects of METH on microglial activation in striatal of mice. Dizocilpine ((+)-MK 801) (0.05, 0.2 mg/kg, i.p.) attenuates subsequent cocaine-primed reinstatement without disruption in rats. Dizocilpine (MK 801) (0.2 mg/kg, i.p.) prior to two reactivation sessions in the home cage shows no suppression on subsequent cocaine-primed reinstatement. Dizocilpine (0.03, 0.1, 0.3 and 1 mg/kg, i.p.) significantly increases the ambulation of mice at 0.3 and 1 mg/kg, but not at 0.03 and 0.1 mg/kg.

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!

FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.

How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
Where is your factory located How can I visit the factory
Our factory located in WEIFANG, China. It is only two hours from QINGDAO.

6. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.

7. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,

8. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

10. How do you treat quality complaint

First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.