CasNo.42461-84-7,Flunixin meglumin,(42461-84-7) Suppliers

1 Kilogram	FOB Price: USD 110.0000

Min.Order :1 Kilogram
Purity: 98%
Payment Terms : D/P,T/T

Keywords

Flunixin meglumin best offer CAS 42461-84-7 Flunixin meglumin manufactuer

Quick Details

Appearance:White crystalline powder
Application:Veteinary pharmaceutical
PackAge:25kg 10kg,5kgs
ProductionCapacity:500|Kilogram|Week
Storage:Dry and cool condition
Transportation:By air by sea or express

Superiority:

Flunixin meglumin
Flunixin meglumine ;Flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. It is a potent inhibitor of the enzyme cyclooxygenase. It has demonstrated biological activity in the following areas:

Analgesia (loss of pain). Flunixin meglumine demonstrated potent analgesic activity in laboratory studies with mice, rats, and monkeys. Parenterally, flunixin meglumine showed anti-writhing activity in mice equal to pentazocine and was more potent than meperidine and codeine. In the rat yeast paw test, it was significantly more potent than pentazocine, meperidine, and codeine. In monkeys, flunixin meglumine produced analgesia comparable to a clinically effective dose of morphine. In the horse, it has been shown to be an effective treatment of pain associated with colic. In contrast to narcotic agents, its analgesic effects were not antagonized by naloxone, tolerance did not develop, and cross-tolerance to codeine did not occur. These results show that flunixin meglumine is an effective analgesic in animals, and drug dependence liability does not occur.

Details:

Testing Items	Specifications	Results
Appearance	White to almost white, crystalline powder	Conforms
Solubility	Freely soluble in water and methanol, paractically insoluble in acetone	Conforms
Identification 1	Infrared absorption:197M;U ltraviolet absorption:197U	Conforms
Identification 2	Water: free soluble;Ethanol(96%):free soluble Ethyl acetate: practically insoluble	Conforms
Melting Point	137~140℃	137.5~138.5
PH	5 %(W/V)water solution:7.0~9.0	8.2
Related Substances	2-chloropyridine-3carboxylic acid ≤0.2%	Undetected
	2-methyl-3-(trifluoromethyl)aniline ≤0.2%	Undetected
	Ethyl 2-chloropyridine-3-carboxylate ≤0.2%	Undetected
	Ethyl 2-[[2-methyl-3-(trifluoromethyl) Phenyl]amino]pyridine-3-carboxylate ≤0.2%	Undetected
Impurities	1. Single impurity: not more than 0.2%	Conforms
	2. Unknown impurity: not more than 0.2%	Conforms
	Total impurities(1~2): not more than 0.5%	Conforms
Specific optical rotation	-9.0°~ -12.0°	-10.3°
Solvent residue	Isopropanol: not more than 0.5%	Conforms
	Ethanol: not more than 0.5%	Conforms
Bacterial endotoxins	Not more than 4.54 EU/mg	0.1 EU/mg
Loss on drying	≤0.5%	0.2%
Sulphated ash	≤0.1%	0.05%
Residue on ignition	≤0.2%	0.1%
Colour of solution	Clear,less coloured than reference solution y6,b.p.(Vet)	Conforms
Clarification	1.2g funixin meglumine/8.8g water	transparent
Explanation	Micronisarion 200±20um
Assay (HPLC)	99.0~101.0%	99.64%
Conclusion	Comply with USP 37/EP7/BPV2012

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