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Tolvaptan Tolvaptan Intermediate 150683-30-0
Product: Tolvaptan Intermediate
Chemical name: 7-Chloro-1,2,3,4-Tetrahydrobenzo[b]Azepin-5-one[CAS:160129-45-3]
Batch No: 20101019-2
Manufacturing Date: Oct., 2010
Expiry Date: Oct., 2012
Analysis report number: 20101019-2
Quantity: 3.0 Kgs
Items Specifications Results
Appearance: light yellow or green crystalline powder Complies
Solubility: freely soluble in absolute methanol,absolute alcohol and ethyl acetate,slightly soluble in ethyl ether,practically in soluble in water Complies
Identification: HPLC Complies
Melting Point: 95~105℃ 100~102℃
Total impurity: 2.0%max. 0.6%
Single impurity: 1.0%max. 0.14%
Loss on drying: 1.0%max. 0.6%
Residue on ignition: 0.1%max. 0.05%
Assay: 98.0%min. 99.4%
Conclusion:It Complies with the Enterprise’s Standard .
HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture.
With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives.
Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support.
Custom manufacture
Thinkchem is good at offering contract manufacture and custom synthesis under confidential agreement timely and effectively, and providing sales service from grams ,kilograms to multi-tons particularly for pharmaceuticals and their intermediates discovery and development. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.
Staff
Thinkchem is composed of chemical technicians, analytical chemists, organic chemists, and chemical engineers educated in leading universities in china. Our staff is supported by a group of consultants from academia with expertise in chemical synthesis and analytical chemistry.
Items Specifications Results
Appearance: white or off-white crystalline powder Complies
Identification: HPLC&IR Complies
Melting point: 210~225℃ 214~216℃
Loss on drying: 0.5%max. 0.2%
Residue on ignition: 0.1%max. 0.03%
Heavy metals: 20ppm max. Complies
Related substance:
Total impurity: 1.0%max. 0.3%
Single impurity: 0.5%max. <0.1%
Assay(on the dried basis): 99.0~101.0% 99.7%
Storage:Keep in dark place,<20℃.
Conclusion:It Complies with the Enterprise’s Standard.
1. Well-trained professional sales team dedicated to source, audit and export.
2. Well-trained R & D team equipped with new knowledge, new ideas and new insights to support product development and innovation.
3. Well-established partnership with major pharmaceutical and chemical companies in china.
4. Wide range of products and efficient regulatory documentation offered to customers.
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