Amlodipine besilate...

Amlodipine besilate 111470-99-6

Amlodipine besilate 111470-99-6

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99% min
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

111470-99-6 Amlodipine besilate Amlodipine besilate

Quick Details

  • Appearance:White Crystalline Solid
  • Application:For Organic Synthesis use
  • PackAge:25kg plastic drum
  • ProductionCapacity:10|Metric Ton|Month
  • Storage:room temperature
  • Transportation:AS PEE MSDS

Superiority:

Amlodipine besilate Basic information
Product Name: Amlodipine besilate
Synonyms: 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate;AMLODIPINE BENZENESULFONATE;AMLODIPINE BESILATE;AMLODIPINE BESYLATE;NORVASC;3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,;4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
CAS: 111470-99-6
MF: C26H31ClN2O8S
MW: 567.05
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Amlodipine;Aromatics;Dihydropyridine;Heterocycles;BENICAR;AZD929
Mol File: 111470-99-6.mol
Amlodipine besilate Structure

 

Details:

 
 
Amlodipine besilate Chemical Properties
mp  199-201°C
storage temp.  Store at RT
solubility  DMSO: 20 mg/mL
form  solid
color  white
CAS DataBase Reference 111470-99-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  US7967700
Hazardous Substances Data 111470-99-6(Hazardous Substances Data)
 
 
Amlodipine besilate Usage And Synthesis
Chemical Properties White Crystalline Solid
Usage A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Usage Angiotensin II inhibitor prodrug, antihypertensive
Usage Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Biological Activity L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).

 

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