Atorvastatin calciu...

Atorvastatin calcium 134523-03-8

Atorvastatin calcium 134523-03-8

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1 Metric Ton

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  • Min.Order :1 Metric Ton
  • Purity: 99% min
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

134523-03-8 Atorvastatin calcium C66H68CaF2N4O10

Quick Details

  • Appearance:white powder
  • Application:ORGANIC CHEMITRY
  • PackAge:As your request
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AS PER MSDS

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Atorvastatin calcium 134523-03-8

Atorvastatin calcium Basic information
Product Name: Atorvastatin calcium
Synonyms: LIPITOR;ATORVASTATIN CALCIUM SALT;ATORVASTATIN CALCIUM;ATORVASTATIN CA;[r-(r*, r*)]-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylaminocarbonyl)-1h-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid calcium salt;1h-pyrrole-1-heptanoicacid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methy;calciumsalt(2:1),(r-(r*,r*))-lethyl)-3-phenyl-4-((phenylamino)carbonyl);ci-981
CAS: 134523-03-8
MF: C66H68CaF2N4O10
MW: 1155.36
EINECS: 200-659-6
Product Categories: Active Pharmaceutical Ingredients;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Atorvastatin;Aromatics;Chiral Reagents;Pfizer compounds;Pharmaceutical intermediates;Isotope;LIPITOR;Cardiovascular APIs;Antilipemic agent;API
Mol File: 134523-03-8.mol
Atorvastatin calcium Structure

 

Details:

Atorvastatin calcium 134523-03-8

Atorvastatin calcium Chemical Properties
mp  176-178°C
storage temp.  Store at +4°C
CAS DataBase Reference 134523-03-8(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,T,F
Risk Statements  20/21/22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  26-36-45-36/37-16-7
MSDS Information
 
 
Atorvastatin calcium Usage And Synthesis
Chemical Properties White Crystalline Powder
Usage A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia
Usage A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Usage antihyperlipidemic, HMGCoA reductase inhibitor
Usage DMSO and EtOH soluble
Usage The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease.
Biological Activity Potent HMG-CoA reductase inhibitor (IC 50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model.

 

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