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Keywords
147-24-0 DiphenhydraMine hydrochloride C17H22ClNO
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Details:
| Diphenhydramine Hydrochloride Basic information |
| Product Name: | Diphenhydramine Hydrochloride |
| Synonyms: | 2-(diphenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride;2-(diphenylmethoxy)-n,n-dimethyl-ethylaminhydrochloride;Actifed;alpha-Hydroxydiphenylmethane-beta-dimethylaminoethyl ether hydrochloride;alpha-hydroxydiphenylmethane-beta-dimethylaminoethyletherhydrochloride;Ambenyl;BAX;Benacine |
| CAS: | 147-24-0 |
| MF: | C17H22ClNO |
| MW: | 291.82 |
| EINECS: | 205-687-2 |
| Product Categories: | Anilines, Aromatic Amines and Nitro Compounds;API intermediates;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Histamine receptor;BENADRIL;Other APIs;On the central nervous activity inhibition of sedative hypnotic effect;API |
| Mol File: | 147-24-0.mol |
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| Diphenhydramine Hydrochloride Chemical Properties |
| mp | 168-172 °C |
| storage temp. | Desiccate at RT |
| Water Solubility | 1000 g/L |
| Merck | 3309 |
| Stability: | Stable, but slowly darkens upon exposure to light. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 147-24-0(CAS DataBase Reference) |
| NIST Chemistry Reference | diphenhydramine hydrochloride(147-24-0) |
| EPA Substance Registry System | Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride(147-24-0) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-39/23/24/25-23/24/25-11 |
| Safety Statements | 36-45-36/37-16-7 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | KR7000000 |
| MSDS Information |
| Provider | Language |
|---|---|
| N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Diphenhydramine Hydrochloride Usage And Synthesis |
| Chemical Properties | white crystalline powder |
| Usage | Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic. |
| Usage | antihistamine, sedative, treatment of allergic |
| Usage | H1-Histamine receptor antagonist. Antihistaminic; sedative, hypnotic |
| General Description | White or almost-white crystalline powder. Odorless with a bitter numbing taste. pH (5% aqueous solution) 4-6. |
| Air & Water Reactions | Water soluble. Aqueous solutions are acidic. |
| Reactivity Profile | N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride gives acidic solutions in water. Neutralizes bases. May react with strong oxidizing and strong reducing agents. May catalyze organic reactions. Slowly darkens on exposure to light. |
| Fire Hazard | Flash point data for N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride are not available; however, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride is probably combustible. |
| Biological Activity | H 1 receptor antagonist. Antihistamine. |
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