2068-78-2 Vincristine sulfate C46H58N4O14S
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Vincristine sulfate Basic information |
Product Name: | Vincristine sulfate |
Synonyms: | VINCRISTINE SULFATE;VINCRISTINE SULFATE, APOCYNACEAE SPECIES;VINCRISTINE SULFATE SALT;VINCRISTINE SULPHATE;VCR;VCR, LEUKOCRISTINE SULFATE;VCR SULFATE;22-oxo-vincaleukoblastinsulfate(1:1)(salt) |
CAS: | 2068-78-2 |
MF: | C46H58N4O14S |
MW: | 923.04 |
EINECS: | 218-190-0 |
Product Categories: | Alkaloids;API;VINCRISTINE SULPHATE;Intermediates & Fine Chemicals;Pharmaceuticals;Additional Affinity PurificationRecombinant Protein Expression and Analysis;Plant Proteomics;Protein Purification;Purification and Detection;V5;API's;Caspases/Apoptosis;Signalling;Chiral Reagents;Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;CLARINEX;Antineoplastic;Anti-cancer & immunity;Inhibitors |
Mol File: | 2068-78-2.mol |
Vincristine sulfate Chemical Properties |
mp | 300 °C |
bp | 273-281 °C |
storage temp. | 2-8°C |
form | lyophilized powder |
Water Solubility | >=1 g/100 mL at 24 ºC |
EPA Substance Registry System | Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt)(2068-78-2) |
Safety Information |
Hazard Codes | T |
Risk Statements | 61-36/37/38-63-23/24/25-68-62-25 |
Safety Statements | 22-24/25-53-45-37/39-26-36/37/39-36/37 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | OH6340000 |
F | 8-10 |
HazardClass | 6.1(a) |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
Leurocristine sulfate salt | English |
ACROS | English |
SigmaAldrich | English |
Vincristine sulfate Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. |
Usage | H1-antihistamine |
General Description | An anticancer drug. White to slightly yellow, amorphous or crystalline powder. Sensitive to light. Odorless. pH (0.1% solution) 3.5 - 4.5. |
Air & Water Reactions | Very hygroscopic. Water soluble. |
Reactivity Profile | Sensitive to hydrolysis, oxidation and heat. Incompatible with strong oxidizing agents. . |
Fire Hazard | Flash point data for Vincristine sulfate are not available; however, Vincristine sulfate is probably combustible. |
Biological Activity | Anticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells. |
Vincristine sulfate Preparation Products And Raw materials |
Preparation Products | DESACETYLVINBLASTINEAMIDE |
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