Methyl 2-hydroxyethyl cellulose

Details:

Product Name: Methyl 2-hydroxyethyl cellulose
Synonyms: Cellulose,2-hydroxyethylmethylether;'Tylose'® MH 300;Hydroxythyl Methyl Cellulose;HydroxythylMethylCellulose(Hemc);HEMC;HYDROETHYLMETHYL CELLULOSE (HEMC);METHYL HYDROXYETHYL CELLULOSE (20-40CPS: 2% IN WATER);Methyl Hydroxyethyl Cellulose (20-40mPa.s, 2% in Water at 20deg C)
CAS: 9032-42-2
MF: C2H6O2·xCH4O·x
MW: 0
EINECS:
Product Categories: Cellulose;Natural Polymers;Polymer Science;Materials Science;Natural Polymers;Polymer Science;Polymers;construction
Mol File: Mol File
Methyl 2-hydroxyethyl cellulose Structure
Methyl 2-hydroxyethyl cellulose Chemical Properties
density  1.28-1.30 g/cm3 (20℃)
storage temp.  Store below +30°C.
solubility  H2O: 20 mg/mL, soluble
EPA Substance Registry System Cellulose, 2-hydroxyethyl methyl ether (9032-42-2)
Safety Information
WGK Germany  1
Autoignition Temperature >360 °C
HS Code  3912 39 85
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
MSDS Information
Provider Language
SigmaAldrich English
Methyl 2-hydroxyethyl cellulose Usage And Synthesis
Chemical Properties soluble in cold water, flocculates at elevated temperatures
Chemical Properties A white, yellowish-white or grayish-white powder or granules, hygroscopic after drying.
Uses Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.
Pharmaceutical Applications Hydroxyethylmethyl cellulose is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations. It has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.
Safety Hydroxyethylmethyl cellulose is used as an excipient in various oral and topical pharmaceutical preparations, and is generally regarded as an essentially nontoxic and nonirritant material.
storage Hydroxyethylmethyl cellulose is hygroscopic and should therefore be stored under dry conditions away from heat.
Regulatory Status GRAS listed. Included in nonparenteral medicines licensed in Europe (oral suspensions, tablets, and topical preparations).