DAPT

DAPT

DAPT

Min.Order / FOB Price:Get Latest Price

1 Metric Ton

Negotiable

  • Min.Order :1 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,T/T

Keywords

208255-80-5 DAPT 208255-80-5

Quick Details

  • Appearance:solid
  • Application:intermediate
  • PackAge:as per buyers
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:R.T.
  • Transportation:by air/sea

Superiority:

Good quantity 

DAPT Basic information
Product Name: DAPT
Synonyms: LY-374973, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester;γ-Secretase Inhibitor IX;N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethylester;SC-201315;(2S)-N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-2-phenylglycine tert-butyl ester;DAPT (enzyme inhibitor);GSI-IX;DAPT (GSI-IX)
CAS: 208255-80-5
MF: C23H26F2N2O4
MW: 432.464
EINECS:  
Product Categories: Angiogenesis and Metastasis;Protease inhibitor;Inhibitor;GSI-IX;Inhibitors
Mol File: 208255-80-5.mol
DAPT Structure

 

Details:

DAPT Chemical Properties
density  1.213
storage temp.  2-8°C
solubility  DMSO: ~18 mg/mL
form  solid
color  white
 
Safety Information
WGK Germany  3
MSDS Information
 
 
DAPT Usage And Synthesis
Usage DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells
Biological Activity Inhibitor of γ -secretase; causes a reduction in A β 40 and A β 42 levels in human primary neuronal cultures (IC 50 values are 115 and 200 nM for total A β and A β 42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo . Does not effect APP α and APP β levels. Blocks Notch signaling in hybrid human-mouse foetal thymus organ culture (FTOC). Activity causes neural cells to commit to neuronal differentiation

 

View All
Visit Store

You Might Also Like

Related Searches

Contact Supplier

Confirm to collect the product to my collection?

OKCancel

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View