Oleanic acid

Details:

1. To reduce liver injury: the oleanolic acid is pentacyclic triterpenoids, which has obvious protective effect on the acute chronic liver injury caused by carbon tetrachloride. After treatment, the enlarged mitochondria and the expanded rough endoplasmic reticulum were restored. It can also be used to reduce the degeneration, necrosis and inflammatory response of liver cells with acute and chronic liver injury. In the liver, triglycerides are reduced and the glycogen is increased.

2. Decreased serum glutamate transaminase activity: the oleanolic acid had obvious enzymes for acute, chronic hepatitis and liver cirrhosis.

3. Decreased serum r-globulin and was consistent with the liver related to inflammatory response seen in the histological observation.

4. Promote the regeneration of hepatocytes: the lepid-pectic acid can promote the number of nuclear fission phase of rat residual liver, and the regeneration rate is higher than the control group, suggesting the effect of promoting cell regeneration.

5. Reduce the cerebral homogenicity in rats with liver cirrhosis: due to the obvious decline in the level of cerebral homogenicity, the production of pseudo neurotransmitter can be suppressed, so it is beneficial to the prevention and control of hepatic encephalopathy.

6. Inhibiting liver fiber hyperplasia: oleanolic acid treatment of liver fibrosis in rats, hepatic fiber hyperplasia serious and significantly reduce, reduce liver collagen content, prompt has the effect of prevention and treatment of liver cirrhosis.

7. Oleanolic acid in mice mononuclear phagocyte system, macrophage phagocytosis and experimental arthritis has obvious inhibitory effect, but to the opposite sex have an impact on the humoral immune function and the antigen cells. Enhance immunity and inhibit S180 growth.

8. There are protective effects on chromosome damage, prevention of experimental atherosclerosis, and correction of protein metabolism disorder. [5]