CasNo.211914-51-1,Dabigatran,(211914-51-1) Suppliers

0 Metric Ton	Negotiable

Min.Order :0 Metric Ton
Purity: 98% min

Keywords

Dabigatran BIBR 953;BIBR 953ZW;BIBR953;BIB-953 211914-51-1

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Application:
PackAge:5mg;10mg;50mg;
ProductionCapacity:50-100|Metric Ton|Day
Storage: -20℃
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Dabigatran

DabigatranDabigatran(BIB-953; BIBR 953ZW) is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. IC50 Value: 4.5 nM (Ki); 10 nM(Thrombin-induced platelet aggregation) [1] Target: thrombin in vitro: Dabigatran selectively and reversibly inhibited human thrombin(Ki: 4.5 nM) as well as thrombin-induced platelet aggregation (IC(50): 10 nM), while showing no inhibitory effect on other platelet-stimulating agents.Thrombin generation in platelet-poor plasma (PPP), measured as the endogenous thrombin potential (ETP) was inhibited concentration-dependently (IC(50): 0.56 microM).

url：www.medchemexpress.cn/dabigatran.html

Details:

Dabigatran

DabigatranDabigatran(BIB-953; BIBR 953ZW) is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. IC50 Value: 4.5 nM (Ki); 10 nM(Thrombin-induced platelet aggregation) [1] Target: thrombin in vitro: Dabigatran selectively and reversibly inhibited human thrombin(Ki: 4.5 nM) as well as thrombin-induced platelet aggregation (IC(50): 10 nM), while showing no inhibitory effect on other platelet-stimulating agents.Thrombin generation in platelet-poor plasma (PPP), measured as the endogenous thrombin potential (ETP) was inhibited concentration-dependently (IC(50): 0.56 microM).

url：www.medchemexpress.cn/dabigatran.html