Add time:07/20/2019         Source:sciencedirect.com

The review (Part 1) deals with the synthesis of 2-pyridone methides and benzo-fused analogs. Methides that are unsubstituted at the nitrogen atom are mainly synthesized from the corresponding pyridine bases by reactions at o- or α-positions, from N-oxides or by ring formation or transformation. N-Substituted so-called anhydrobases mostly originate from quaternary salts either by deprotonation or by reactions at o- or α-positions.

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