Add time:07/23/2019         Source:sciencedirect.com

Hirudin PA54–66 and related hirudin fragment analogs were synthesized and assessed for their inhibition of thrombin-induced fibrin-clot formation in plasma. Pro58 and Ala63 -Tyr64 modifications in the hirudin sequence resulted in increased antithrombin potency, whereas Asp, Ala and Tyr individual substitutions each resulted in a loss of potency.

We also recommend Trading Suppliers and Manufacturers of HIRUDIN (55-65) (SULFATED) (cas 109528-50-9). Pls Click Website Link as below: cas 109528-50-9 suppliers