Add time:07/21/2019 Source:sciencedirect.com
The sequence Aib-Gly-Aib which corresponds to the N-terminus of the microheterogeneous peptide antibiotic trichotoxin has been studied crystallographically in the context of different protecting groups. Peptides Ac-Aib-Gly-Aib-OH (A) and Z-Aib-Gly-Aib-OH (B) form β-turns. Both peptides show a remarkable conformational flexibility forming a large variety of β-turns of different types.
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