Carbonylative formation of N-acetyl-2,6-difluorobenzamide through N–H bond activation of 2,6-difluorobenzamide with Ni(II) complex supported with phosphine ligands-Science-Chemical Encyclopedia-lookchem

Carbonylative formation of N-acetyl-2,6-difluorobenzamide through N–H bond activation of 2,6-difluorobenzamide with Ni(II) complex supported with phosphine ligands
Add time:07/21/2019 Source:sciencedirect.com

Fluorinated imide, N-acetyl-2,6-difluorobenzamide (C6H3F2-2,6)C(O)NHC(O)Me 2, could be obtained through one-pot reaction of NiMe2(PMe3)3 with 2,6-difluorobenzamide (C6H3F2-2,6)C(O)NH2 1 in CO atmosphere. A postulated reaction mechanism via N–H bond cleavage and carbonylative reductive elimination on nickel center was partly experimentally confirmed. An important intermediate (C6H3F2-2,6)C(O)HNNiMe(PMe3)2 3 was isolated and structurally characterized.

We also recommend Trading Suppliers and Manufacturers of N-(2-Fluoropyridine-4-carbonyl)-L-proline (cas 123412-43-1). Pls Click Website Link as below: cas 123412-43-1 suppliers

Prev:The biomimetic iron-mediated degradation of ARTEFLENE (cas 123407-36-3) (Ro-42-1611),an endoperoxide antimalarial: Implications for the mechanism of antimalarial activity
Next: On the anomalous vibration spectra and OH⋯N bond dictated structure of 3-fluoroisonicotinic acid)

Click to view details

Encyclopedia