Add time:07/11/2019         Source:sciencedirect.com

The unprecedented annulation/hydroxyfluorination of propargylic carbamates to give 4-fluoromethyl-4-hydroxy-oxazolidinones was investigated. The reaction was effectively promoted by NaHCO3 and/or silver catalysis. The peculiar behavior of propargylic carbamates bearing a chiral steroidal moiety is described. Extensions and limitations of the procedure with respect to urea derivatives, homopropargyl compounds, internal alkynes and one-pot transformations of propargylic alcohols with isocyanates are reported.

We also recommend Trading Suppliers and Manufacturers of prop-2-yn-1-yl (4-chlorophenyl)carbamate (cas 5396-86-1). Pls Click Website Link as below: cas 5396-86-1 suppliers