Add time:07/23/2019         Source:sciencedirect.com

The cytotoxic compound, virgaureasaponin 1, was converted using several optimized enzyme-catalysed hydrolyses to the 28-O-β-d-xylopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 2)-β-d-fucopyranoside (2), and the 28-O-α-l-rhamnopyranosyl-(1 → 3)-β-d-xylopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 2)-β-d-fucopyranoside (3) and 28-O-β-d-xylyopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 2)-β-d-fucopyranoside (4) both lacking the glucose moiety at C-3 of the aglycone. The terminal rhamnose of the acylglycosidic bonded tetrasaccharide was cleaved by naringinase to give compound 2. The new acylglycosides 3 and 4 were obtained with the help of a relatively crude β-glucuronidase preparation, but the cleavage of the sapogenin bonded glucose was impossible using several β-glucosidase preparations directly. These derivatives were used for the investigation of the relationship between the saponin carbohydrate structure and their cytotoxic activity.

We also recommend Trading Suppliers and Manufacturers of virgaureasaponin 3 (cas 112509-54-3). Pls Click Website Link as below: cas 112509-54-3 suppliers