Add time:07/23/2019 Source:sciencedirect.com
3-Arylisoxazoles and 3-aryl-2-isoxazolines are versatile building blocks in organic chemistry. They are components of a wide number of pharmaceutical products and biologically active molecules. This chapter describes developments in the chemistry of these heterocycles, focusing on synthetic methods and reactivity studies published in the years 2005–2016. Particular attention is given to the regioselectivity of synthetic methods and their application to the preparation of pharmacological active compounds.
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