Add time:07/24/2019         Source:sciencedirect.com

The adsorption of N-methyl 8-hydroxy quinoline methyl sulphate—a drug generally used to protect from sunburn—by natural and acid-treated sepiolite, has been investigated. Acid treatment led to partial dissolution of the fibres of the clay, mainly in the external surface of the crystallites. Incorporation of the drug decreased the amount of water adsorbed, leading to a strong interaction between the drug and the clay, but upon acid treatment the interaction seemed to weaken. Clay-drug complexes formed by adsorption from the drug aqueous solutions and by mechanical mixing of the components in the solid state served as good sunburn shields, as indicated by the spectra of these materials in the visible-ultraviolet range of the spectrum.

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