Add time:07/26/2019 Source:sciencedirect.com
The crystal structure of Seratrodast (cas 112665-43-7) (AA-2414), a potent thromboxane A2 (TXA2) receptor antagonist, served as starting point to docking studies with the modeled human TXA2 receptor. This structural approach provides rational basis for the design of new antagonists within the aryl sulfonamide family.
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