Add time:07/23/2019         Source:sciencedirect.com

Background/aimsPyrimidines have a long and distinguished history extending from the days of their discovery as important constituents of nucleic acids to their current use in medicinal chemistry. As a part of project devoted to the development of pyrimidine analogs as antimicrobial agents we have focused our attention on synthesis of C5/C6 substituted pyrimidine derivatives, specifically C6 substituted pyrimidine analogs which have emerged as potent molecule in recent years.

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